Panama City Spa Hotel

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Top Panama City Spa Hotel

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
8.8 out of 10, Excellent, (885)
"I will definitely stay here again. The staff went beyond the call of duty to help non spanish speaking customers"
The price is HK$1,160
HK$1,276 total
includes taxes & fees
8 Dec - 9 Dec
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (514)
"Beautiful resort with very helpful and friendly staff. The food was amazing! I’ll definitely be back."
The price is HK$1,315
HK$1,447 total
includes taxes & fees
13 Dec - 14 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"I really enjoyed my time at the Marriott and im looking forward to coming back soon "
The price is HK$1,121
HK$1,233 total
includes taxes & fees
22 Dec - 23 Dec
Marriott Panama Hotel
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"It is a great hotel, with great staff and superb personalized service. Totally recommended!"
The price is HK$1,323
HK$1,455 total
includes taxes & fees
21 Dec - 22 Dec
Bristol Panama, a Registry Collection Hotel
W Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Lo único que puedo decir es que el baño mejor la ducha tiene moho. Todo lo demás estuvo muy lindo y bueno"
The price is HK$990
HK$1,089 total
includes taxes & fees
20 Dec - 21 Dec
W Panama
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (337)
"This is a fantastic property with amazing attention to detail in every aspect of the operation. A lovely spot to spend a few days! "
The price is HK$2,277
HK$2,504 total
includes taxes & fees
19 Dec - 20 Dec
Sofitel Legend Casco Viejo, Panama City
Sheraton Grand Panama
4.0 star property
8.4 out of 10, Very good, (816)
"The front desk staff was extremely hepful with suggestions of local tours and experiences. They were also quite thoughtful- sent a birthday cake to my mom's room. They added joy to our overall experience "
The price is HK$1,062
HK$1,169 total
includes taxes & fees
23 Nov - 24 Nov
Sheraton Grand Panama
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"The hotel was modern and well maintained. Staff were friendly and helpful. Loved how central it was and close to everything."
The price is HK$1,083
HK$1,192 total
includes taxes & fees
6 Dec - 7 Dec
Hilton Panama
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"This hotel did not disappoint. The staff was friendly offering round the clock service. All of the property amenities were excellent, with breathe taking views. If my itinerary wasn’t so busy for my stay, I would have loved to just stay at the hotel longer to relax. I will def be back"
The price is HK$1,177
HK$1,294 total
includes taxes & fees
6 Dec - 7 Dec
JW Marriott Panama
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (763)
"Beautiful. Great. 10/10. Had a cancelled flight and this was great and I’m a really great area. I’d stay here again for a couple of nights. "
The price is HK$953
HK$1,049 total
includes taxes & fees
25 Nov - 26 Nov
Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Panama City
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.

Frequently asked questions

Looking to holiday at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Make sure you enjoy the cafes during your stay. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a rooftop terrace. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in Panama City include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels are there in Panama City?
Expedia has 19 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Multicentro Panama.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas and offer services including facials and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.