Panama City Car Rental

Search and Compare from Car Companies in Panama City

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.

Frequently asked questions

Can I rent a car from Tocumen Intl. Airport (PTY)?
Thrifty Car Rental and Sixt are within a short commute of Tocumen Intl. Airport (PTY). After landing, it won’t be long before you’re on the road.
What happens if I need to cancel my Panama City car reservation?
If you have to make changes to your itinerary, almost all prepaid bookings are eligible for a complete refund. Just let us know more than six hours in advance of the arranged pickup time. Check the policy for any exclusions. Your itinerary will have more details, or jump onto our Customer Service Portal for more info.
Why should I rent a Panama City car with Expedia?
There are savings for the savvy traveler with Expedia. Whether you’re after something that’ll fit the whole family or just the two of you, compare the deals from the car rental companies in Panama City. Our member exclusive offers and discounts will help you land the lowest price possible. Combine your vehicle with your flights and hotel for even greater savings. On the lookout for things to do in Panama City? Add some tours to your vacation package later on!
How do I find the best car rental deals in Panama City with Expedia?
Expedia makes it easy and fast to compare costs, offers and rental companies, and to check reviews. Bundle your Panama City car rental with hotel or flight bookings to make even bigger savings.
What do you need to rent a car in Panama City?
Renting a car in Panama City is easy. Usually, all that’s required is a current driver’s license and a credit card in the same name. Once you’ve found a great set of wheels, check your policy to ensure there are no additional requirements before pickup.
Can I rent a car for a month or longer in Panama City?
Yes, and you can find your ideal ride on our long-term car rental deals page. Simply enter your trip dates and we’ll show you amazing options from numerous quality suppliers.
Where can I find a Panama City car rental if I am younger than 25?
This will depend on the rental companies that are in Panama City. They often have different policies when it comes to minimum ages. If you’ve found a supplier that does cater to drivers under 25 years of age, bear in mind that extra fees may apply. Conduct some research into what those charges could be before booking your rental car.