Photo by Ryan Coleman

Sikeston hotels from HK$454

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Sikeston hotels

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (226)
"I enjoyed the Casino Access, Nice clean large rooms. Peaceful atmosphere. "
The price is HK$747
HK$842 total
includes taxes & fees
29 Apr - 30 Apr
The Riverview

Tru By Hilton Cape Girardeau

2.5 star property
9.8 out of 10, Exceptional, (8)
"The manager wwnt above and beyond to make ua comfortable, the hotel had juat opened so everything was new and super clean, a very 21st century dwelling and very impressive The rooms however do not have cupboards and drawers for clothing and stuff, but overally it was nice. "
The price is HK$784
HK$893 total
includes taxes & fees
4 May - 5 May
Tru By Hilton Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Was nice hotel. Food was good. Overall great experience "
The price is HK$733
HK$827 total
includes taxes & fees
20 Apr - 21 Apr
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (538)
"Loved the healthy options for breakfast, also the spaciousness of the room and the big comfortale chair with the extra high foot rest"
The price is HK$646
HK$699 total
includes taxes & fees
16 Apr - 17 Apr
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Will definitely stay there again!!"
The price is HK$799
HK$901 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Bed was comfortable Room very clean Breakfast was good "
The price is HK$698
HK$738 total
includes taxes & fees
23 Apr - 24 Apr
Drury Inn & Suites Jackson MO

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (100)
"Good"
The price is HK$721
HK$814 total
includes taxes & fees
4 May - 5 May
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Breakfast below average coffee good "
The price is HK$558
HK$630 total
includes taxes & fees
20 Apr - 21 Apr
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Excellent costumer service and very clean facility. This is my number one choice hotel while visiting family in Sikeston. Nice kick back dinner with great breakfast options. Well lighted parking lot! "
The price is HK$768
HK$883 total
includes taxes & fees
20 Apr - 21 Apr
Drury Inn & Suites Sikeston, MO

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (703)
"Would go back again and refer to friends!"
The price is HK$870
HK$982 total
includes taxes & fees
4 May - 5 May
Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"This hotel is very comfortable clean and staff goes out of their way to be friendly!!!! I love staying at this hotel!"
The price is HK$663
HK$762 total
includes taxes & fees
23 Apr - 24 Apr
Pear Tree Inn Sikeston

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (408)
"Amazing "
The price is HK$969
HK$1,099 total
includes taxes & fees
4 May - 5 May
Courtyard by Marriott Cape Girardeau Downtown

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (918)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is HK$733
HK$827 total
includes taxes & fees
27 Apr - 28 Apr
Drury Inn & Suites Cape Girardeau

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (330)
"Staff was really nice"
The price is HK$982
HK$1,112 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn Sikeston

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very good, (698)
"Big room on the corner!!"
The price is HK$675
HK$730 total
includes taxes & fees
16 Apr - 17 Apr
Comfort Suites Jackson-Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Absolutely wonderful friendly people great location very clean! I love it "
The price is HK$454
HK$512 total
includes taxes & fees
28 Apr - 29 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1002)
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we were able to have are Yorkie in room at a reasonable charge "
The price is HK$699
HK$796 total
includes taxes & fees
22 Apr - 23 Apr
Best Western Plus Sikeston

Quality Inn

2.5 star property
7.0 out of 10, Good, (564)
"It was okay"
The price is HK$520
HK$586 total
includes taxes & fees
16 Apr - 17 Apr
Quality Inn

Rockwood Inn

2.0 star property
9.8 out of 10, Exceptional, (6)
"Had a wonderful stay at the Rockwood Inn and ready booked additional stay. Perfect location to stay at for football games or any other SEMO event! "
The price is HK$1,166
HK$1,315 total
includes taxes & fees
29 Apr - 30 Apr
Rockwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Sikeston
Save an average of 15% on thousands of hotels when you're signed in

Sikeston and related destinations

Explore Sikeston: its dining, riverfront, university life and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman

Florence awaits: its dining, museums, entertainment and more!

Los Banos awaits: its dining, entertainment, theatre and more!

Photo by Jess. LongestBusRide
Open Photo by Jess. LongestBusRide

Experience romantic Olive Branch: its dining, entertainment, live music and more!

Lima awaits: its university life, dining, cathedral and more!

Photo by throwingsofas
Open Photo by throwingsofas

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best holiday rentals that Sikeston has to offer?

Beautiful location in the secluded woods : This holiday home rental outside of Sikeston offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.

What's the best family accommodation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your family trip. Also, children of all ages will enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What's the best LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best dog-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

What's the best hotel for a golf holiday in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some hotels with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Sikeston.

What is staying in Sikeston like?

Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.

What is there to see in Sikeston?

Favourite places to visit include Central Park, The Book Bug and Sikeston Depot Museum. Additionally, you might want to add Boot Heel Golf Club to your itinerary. Take a look at what more there is to see and do in Expedia's Sikeston guide.

What's the seasonal weather in Sikeston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.